Methyldienolone (MD) is a synthetic oral anabolic steroid that was researched in the 1960's but never sold as a prescription drug. It is fundamentally a nandrolone-based compound, modified from this base hormone in two ways. First, it has been c-17alpha-alkylated (methylated) to protect against hepatic breakdown. This alteration, in of itself, turns the mild-mannered nandrolone into the formidable oral agent methylnandrolone. Next, it has been given a second double-bond at the 9 position, which considerably increases its anabolic and androgenic potency. Methyldienolone actually differs from methyltrienolone, the most potent steroid profiled In this book, only by the lack of a third double-bond (hence the "di" part). Although not actually #2 in the book, methyldienolone is 5 times more potent than Dianabol, 10 times more potent than methyltestosterone, and 13 times more potent than Primobolan®.
Other characteristics of note include an inability to be converted into estrogen, which limits this steroid's potential for related side effects like fat gain, water retention, and gynecomastia. This trait makes it a drug more ideally suited for cutting cycles than bulking ones. However, as a nandrolone based compound, it may have some progestational activity, which can work to intensify the effects of estrogen. Therefore, it may not be the ideal steroid to use with other aromatizable (estrogen producing) compounds, if fat loss and muscle definition are key concerns. Methyldienolone is also only moderately androgenic, with just a modest propensity to trigger oily skin and acne when used in reasonable dosages. Overall, this agent is classified as an "anabolic" and should fall somewhere between the milder nandrolone derivatives and more androgenic orals like Dianabol and Anadrol.
Effective oral daily doses are going to fall in the range of 2-1 Omg per day for men, and under 1 mg daily for women. At this level, one should expect measurable strength and lean tissue gains, which should be accompanied by decent fat loss and minimal side effects. When determining dosage one also needs to respect the fact that methyldienolone is a c-17alpha-alkylated compound, and presents some liver toxicity to its user. For optimal safety it is usually recommended to limit drug duration to no longer than 8 weeks, after which a break is taken from all methylated or ethylated steroids. One might also want to avoid stacking this drug with other liver toxic orals, and instead opt to use an injectable base instead. 5mg per day of methyldienolone combined with 400mg weekly of testosterone cypionate/enanthate or Equipoise® would make an excellent lean-mass stack, while trenbolone (225mg) or Primobolan® (300-400mg) could be used instead for cutting.
Availability of methyldienolone is going to be limited over the next couple of years, due to the recent scheduling of this agent as a class III controlled substance.This agent was manufactured as a nutritional supplement for a brief period of time before the 2004 amendment to the anabolic steroid act was passed, which means there should be a fair amount of leftover supplement available as people take advantage of its increasing value and sell off their pre-ban "stockpiles" The long-term future of this agent remains uncertain, however, as no legitimate drug company has yet to take an interest in it. It is unfortunate to think that this drug may no longer be available in a couple of years.This is a very powerful agent though, and may very well peak the interest of some of the companies looking for a "different" oral to sell. That is, of course, if the consumer market can get over the fact that this drug was once "legal" Although sold openly for a while, MD is indeed still one very powerful, and one very real, steroid.
It is important to note that there may be an issue with methyldienolone "counterfeits" I was made aware that the compound 3,17-dimethyldiendiol (a 3-methylated diol analog of MD) was being manufactured and sold as methyldienolone to various U.S. supplement companies. This was apparently done because of manufacturing troubles, and with the knowledge of some of the buyers, who felt it was "essentially the same thing" Other companies may have been selling this material as MD unwittingly, given the rarity of true "quality control" in the supplement industry (few independently lab test their products).Therefore, those who have noticed poor results from this steroid may not have been using the real thing. I do believe that early manufacturing issues were resolved, and raw methyldienolone has made its way to the market before the passing of the law. Provided you are buying legitimate methyldienolone, you can feel good knowing you have a very rare, structurally unique, and extremely powerful steroid, which few in history were given an opportunity to use.