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As is implied by the given trade name, Prostanozol (demethylstanozololTHP) is an oral anabolic steroid closely related to the highly popular drug Winstrol (stanozolol) in structure. It was introduced to the U.S. sports nutrition market in 2005 as a "post-ban" hormone, distributed openly as a supplement product instead of being regulated as a prescription drug.This is stemming from the fact that it was unknown to lawmakers at the time the 1991 and 2004 anabolic steroid laws were enacted, and as such simply could not be included in them. Although its legal status as a nutritional supplement may be in some question (this is considered a grey-area product), there are no criminal laws against its possession or use (yet). Prostanozol is one of several new legitimate synthetic anabolic/androgenic steroid products to hit the market in 2005, so don't let its quasi-legal status fool you.
Structurally, Prostanozol differs from Winstrol by the removal of the c-17 alpha alkyl group.This modification is responsible for allowing Winstrol to survive first pass metabolism through the liver, so its removal undoubtedly hurts the oral bioavailability of this steroid. In an attempt to compensate for this, an ether group has been added. The ether functions very similarly to an ester when used orally, increasing oil solubility and the likelihood of lymphatic delivery with dietary fats (which bypass the first pass through the liver). This is the same principle that Anabolicum Vister (quinbolone) was developed on. In the case of Prostanozol, however, there is no oil carrier. Without a proper oily carrier, the chance for lymphatic delivery is significantly lowered. This will necessitate a much higher oral dosage than would be needed otherwise, in a process that sort of shotguns the liver with so much steroid that small amounts are bound to slip by. Indeed they do, and despite no carrier and low oral bioavailability, Prostanozol does seem to be working.
Demethylstanozolol (a generic name I simply made up this substance) appears to be a new chemical entity. If a non-methylated stanozolol ever were synthesized and assayed before, I couldn't find any mention of it in the steroid research books. At this time there is little specific information that could be said about its various chemical properties, as there are no assays or studies to make note of. What can be said are some basic things that we can figure out based on its structure. For one, it is unable to convert to estrogen, and as such should not produce related side effects (water retention, gyno, fat buildup). It should be much more of a lean-gainer or cutting drug instead. We also know that no "dihydro" metabolites could be formed from Prostanozol, since this is already a 4,5-dihydro steroid. Its anabolic to androgenic ratio should, therefore, be somewhat balanced, without the strong androgenic aspect of testosterone. Although androgenic side effects are always possible with a steroid, they should require fairly high does. Do keep an eye on fatigue if you plan on taking this drug alone.This side effect is linked to low estrogen levels, as this hormone is responsible for up-regulating brain serotonin.
The main drawback to this steroid is going to be its poor oral bioavailability. Unless an oil-solubilized soft gelatin capsule or injectable solution is formulated, the user is going to be forced to take a considerable dose. For men, this would fall in the range of 100mg-150mg per day just to see a decent effect on lean tissue gain. Higher doses will be needed for a very strong anabolic effect. Feedback on use by females is extremely sparse, but I would expect a single 25mg capsule per day would be a good place to start, upping this slowly by a capsule or two (max) if the desired effect is not reached. When it comes to the oral bioavailability of an unprotected steroid like this, there are going to be strong differences between individuals. One person may need far more or less drug than the next. Therefore, individual dosing pattern will need to be determined as the user becomes accustomed to therapy.
At the time of writing this, Prostanozol is still being sold as a nutritional product in the U.S. Its time on the market, however, is likely to be very short. The FDA and others in the government have already angrily acknowledged that th
ere are new "designer steroids" on the supplement market, and have made clear their intentions on investigating and even prosecuting those misbranding steroid products (drugs) as supplements. The original manufacturer (ALRI) has already discontinued its sale, anticipating FDA action. Other versions (such as Orastane-E by Gaspari Nutrition) are still available, but the future of these products does not look good at all. If you can still find it, one would be advised to purchase it quickly if they had any specific plans on using. It is very likely that this steroid will already be gone from the marketplace by the time you read this.